PRANDIN® repaglinide Tablets FAQ's

Take PRANDIN^® just before you start eating, or up to 30 minutes before the meal. If you miss a dose of PRANDIN^®, don't take it between meals; just take your usual dose before your next meal.

Does PRANDIN^® control after-meal glucose spikes?
When you take PRANDIN^® just before you eat, you help your body release the insulin needed to handle glucose spikes. PRANDIN^® begins to work quickly. PRANDIN^® helps your body release insulin to handle the blood glucose from that meal. PRANDIN^® then leaves your bloodstream quickly, and insulin levels return toward baseline between meals and during the night.

How do you remember to take PRANDIN^® as prescribed?
It's simple: just remember to "treat when you eat." The flexibility of mealtime dosing with PRANDIN^® allows you to plan your medication around your meals instead of planning your meals around your medication.

Safety Information
Prandin is only taken before meals. If you miss a meal you should skip that dose. Just take your usual dose the next time you eat. Prandin is safe to take 2, 3, or 4 times daily before you eat, up to a maximum of 16mg per day, as directed by your doctor.

Is PRANDIN^® safe for everyone with diabetes?
People with type 1 diabetes, people who have diabetic ketoacidosis, and people who are allergic to PRANDIN^® or its inactive (nonmedicine) ingredients should not take PRANDIN^®. (Check with your doctor if you are pregnant or breast-feeding. Studies have not been conducted with pregnant women. Your doctor will decide about your treatment if you have liver or kidney disease).

Can PRANDIN^® cause side effects?
As with any blood-glucose lowering medication, hypoglycemia (low blood glucose) can occur. If you have symptoms of low blood glucose (such as headache, dizziness, tiredness, nervousness or shakiness, or rapid heartbeat), test your blood glucose level right away. If it's low (plasma glucose less than 60 mg/dl), eat a simple carbohydrate food (eg, orange juice, quick-dissolving sugar candies, or glucose tablets, as directed by your doctor or diabetes educator) speak to your doctor or diabetes care team about what is considered "low glucose" for you. If the symptoms don't go away, call your doctor or seek medical attention as needed.

In clinical trials, the most common adverse events leading to discontinuation of PRANDIN^® therapy were hyperglycemia, hypoglycemia, and related symptoms. The most common other side effects reported were cold- and flu-like symptoms, headache, diarrhea, joint ache, and back pain.

Where should you keep your PRANDIN^®?
Store PRANDIN^® at room temperature away from moisture. Always store it in the bottle it came in with the lid on tight, and throw away unused tablets after the expiration date on the label. As with all medications, keep it out of the reach of children.

If you suspect that someone may have taken more than the prescribed dose of PRANDIN^®, contact your local poison control center or emergency department immediately. This medication was prescribed for your particular disease. Don't use it for another condition or give the drug to others.